General & Cosmetic Dermatology
Hyperhidrosis Treatment in Tampa
Excessive sweating — hyperhidrosis — goes far beyond normal perspiration. It can soak through clothing, cause social anxiety, and interfere with daily life. Dr. Sergay offers multiple proven treatments, including prescription-strength antiperspirants, oral medications, and Botox injections for lasting relief.
Dr. Sergay's Approach
Understanding Hyperhidrosis
Hyperhidrosis is defined as sweating that exceeds what your body needs for temperature regulation. It affects approximately 3% of the population and is divided into primary focal hyperhidrosis — which targets specific body areas without a medical cause — and secondary hyperhidrosis, which results from an underlying condition or medication.
Primary hyperhidrosis is the most common type. It typically begins in adolescence or early adulthood and is associated with overactive sympathetic nerve signaling to sweat glands. It tends to be bilateral (both sides equally affected) and can have a significant hereditary component.
This condition significantly impacts quality of life — from avoiding social situations to limiting career choices. Dr. Sergay takes a step-wise approach, beginning with the least invasive options and escalating as needed to achieve meaningful sweat reduction.
Underarms (Axillary)
Most common site
Palms (Palmar)
Affects handshakes & grip
Feet (Plantar)
Often with foot odor
Face & Scalp
Cranial hyperhidrosis
Treatment Options
How Dr. Sergay Treats Hyperhidrosis
Multiple effective treatments exist — from topicals to injections to devices. The right choice depends on which body areas are affected and the severity of sweating.
Prescription Antiperspirants
Prescription-strength aluminum chloride (Drysol, Xerac AC) is the first step for most patients. Applied at night to completely dry skin, these block sweat ducts directly. More effective than any OTC product and the appropriate starting point for axillary and palmar hyperhidrosis.
Botox Injections
FDA-approved botulinum toxin injections block the nerve signals that trigger sweat glands. Extremely effective — reducing sweating by 80–90% in treated areas. Results last 6–12 months. Most commonly used for underarms; can also treat palms and feet. Performed in-office with topical numbing.
Oral Anticholinergics
Medications like glycopyrrolate or oxybutynin reduce sweating throughout the body by blocking acetylcholine signaling. Useful for widespread or facial hyperhidrosis where topical treatment is impractical. Side effects include dry mouth and mild blurred vision at higher doses.
Qbrexza (Glycopyrronium Cloth)
A once-daily prescription medicated cloth (glycopyrronium 2.4%) wiped across the underarms. FDA-approved for primary axillary hyperhidrosis. Provides a convenient, targeted approach without systemic side effects of oral anticholinergics.
Step-Up Approach
Dr. Sergay uses a step-wise protocol — starting with the safest options and advancing as needed. Most patients achieve excellent control with prescription antiperspirants or Botox. Surgical options (sympathectomy) exist but are rarely needed and come with significant risks.
Your Dermatologist
About Amanda Sergay, MD
Board Certified
American Board of Dermatology
Specialties
Medical · Surgical · Cosmetic
Location
South Tampa, FL
Board-Certified Dermatologist · Medical · Surgical · Cosmetic
Amanda Sergay, MD is a board-certified dermatologist committed to excellence in comprehensive dermatological care. Originally from the Tampa area, Dr. Sergay received her undergraduate degree from Emory University and earned her medical degree from the University of Miami Miller School of Medicine.
She completed her residency in dermatology at Mount Sinai St. Luke's-Roosevelt Hospital Center in New York City, where she served as Chief Resident during her final year. Her practice encompasses medical, surgical, and cosmetic dermatology, treating both adults and children.
Dr. Sergay has been named to Tampa Magazine's Top Docs Edition in 2019, 2020, 2021, 2022, 2023, 2024 and 2025, and was twice named to New York Magazine's New York Rising Star list.
Awards & Recognition
Tampa Magazine Top Docs
2019202020212022202320242025Super Doctors
Emory University
Undergraduate
Univ. of Miami Miller
Medical Degree
Mount Sinai NYC
Residency · Chief Resident
Patient Reviews
What Our Patients Say
Real Google reviews from patients who trust Dr. Sergay with their skin health.
“Dr. Sergay was just fabulous. Thorough for our skincare check and so informative. Highly recommend for anyone looking to get an established, yearly dermatologist for skin cancer checks.”
Iris Moore
9 reviews
“Now this is a medical practice done right! I love how they don't play the insurance game and are a privately owned practice. This allows them to provide top notch care and a patient experience that is hard to find anywhere else. Dr. Sergay is extremely thorough during her exams and so kind. Trust her with your care!”
Victoria Hansen
Local Guide · 123 reviews · 144 photos
“Dr. Sergay is awesome! I am a new patient and very much appreciated her approach, thoughtfulness and attention to detail. Highly recommend!”
Chad Panton
Local Guide · 36 reviews · 2 photos
“Warm welcome to a nice office. Seen quickly by very proficient and kind Dr Sergay and staff. Great follow up with care plan and prescriptions. Highly recommended.”
Frank King
5 reviews
“Dr Sergay is wonderful. She's deeply knowledgeable about her field, and also has a wonderful, attentive manner. She and her staff are so caring and responsive. I highly recommend.”
Dana Whiting
3 reviews
“First time appointment — Dr. Sergay was amazing. Very easy to talk to and she told me the choices I had and got the procedure done. Highly recommend.”
Darren Finebloom
Local Guide · 21 reviews
Common Questions
Hyperhidrosis FAQ
Take Control
Stop Letting Sweating Run Your Life
Hyperhidrosis is treatable — and highly effectively so. Dr. Sergay will evaluate your specific pattern and design a plan that gets you real, lasting relief.